PROLARYN PLUS is an injectable implant containing the same aqueous/glycerin/ carboxymethylcellulose gel found in PROLARYN GEL.1 Suspended in the gel are consistently shaped and sized synthetic calcium hydroxylapatite (CaHA) microspheres (diameter range of 25 to 45 μm).1
Over time the gel is dissipated in vivo and replaced with soft tissue growth, while the CaHA remains longer at the site of injection. The result is long-term restoration and augmentation of the vocal folds.1
PROLARYN PLUS initially performs as a bulking agent.
Macrophages start to degrade gel carrier (2–3 months).
New collagen forms. Collagen growth aids in long-term augmentation that may last for a year in many patients. Ultimately, CaHA particles start to degrade and are metabolized by macrophages.